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Additionally, these PUFA-enriched TAMs exhibit heightened lipid-oxidative phosphorylation metabolism, aligning with an M2-like, immune-dampening functionality that hinders cytotoxic CD8+ T-cell infiltration, thereby impairing adaptive immune responses against the tumor

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4C and D) and impaired fatty acid internalization (Fig

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In vitro characterization of FLIP-G Purified sensor protein from E

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We also describe the current roles of ferroptosis in the preclinical treatment of these diseases

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