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[0001516] In one embodiment, the antibody compositions described herein may be conjugated with another compound

It is designed to be more resistant to degradation in the body than angiotensin IV, which allows it to have a longer duration of action

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The human results are mixed, with small open-label studies encouraging but the controlled phase 2 OVERTURE trial missing its primary endpoint, and the larger pivotal trial has finished enrolling with results pending, so for now it is best read as mechanistically promising and clinically unproven