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Therapeutic applications of arsenic binding to proteins Arsenous acid [As(OH) 3 ] formed by dissolving of arsenic trioxide (As 2 O 3 ) was found to be an effective and safe treatment for acute promyelocytic leukemia (APL) in the 1970s

Despite its advantages as an anticancer therapeutic agent, intrinsic or acquired resistance to TRAIL limits the success of TRAIL-based therapies

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

Leukopenia in COVID-19 patients may be related to ferroptosis in leukocytes and suppressed GPX4 caused by SARS-CoV-2 [102].The lack of GPX4 induced the loss ability of GSH be peroxidized to minimize the lipid ROS produced by the Fenton reaction