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Most men notice symptomatic improvements within 4 to 6 weeks if the biochemical response is favorable, though the full benefit to muscle recovery, mood, and libido often takes 8 to 12 weeks to consolidate

In laboratory studies, it is sometimes used alongside other metabolic or mitochondrial research agents, depending on experimental design

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Suzuki Y, Sasagawa I, Itoh K, Ashida J, Ogata T (2002) 5Alpha-reductase type 2 genes in Japanese males do not appear to be associated with cryptorchidism