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Bacteriostatic Water provides a suitable multi-use reconstitution vehicle for PEG MGF and the PEGylation of the MGF E-domain peptide provides aqueous solubility compatible with direct Bacteriostatic Water reconstitution without the acetic acid acidification sometimes required for unconjugated peptides

Recent studies confirmed that daratumumab lacks the ability to induce apoptosis in the absence of crosslinking agents, though the contribution of direct cell death to overall anti-CD38 killing of MM cells in patients remains to be fully characterized [28]

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if not, they may hold steady