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The Abl SH2, Btk SH2 and Lck SH2 domains were produced in LB medium with an N-terminal tag including a His 6 and Glutathione S-transferase (GST), and tobacco etch virus (TEV) protease recognition motifs using the pETM30 vector

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Metformin is a first-line medication for type 2 diabetes that primarily works by reducing glucose production in the liver and improving insulin sensitivity in peripheral tissues