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80 Fernandez-VizarraE.BugianiM.GoffriniP.CarraraF.FarinaL.ProcopioE.et al (2007)

Annals of Emergency Medicine 2005

Consistently with previous studies 8,9 FM19G11-loaded NP treatment in G93A-SOD1 epSPCs led to a significant reduction of several metabolites, including D-glucose, lactic acid, citric acid, and mevalonate, shifting them to levels comparable to those of control cells

Epigenome-wide association studies (EWASs) have revealed stress-induced DNA methylation changes, such as hypermethylation of the NR3C1 (glucocorticoid receptor) gene in the central amygdala, which modulates visceral pain sensitivity in the gutbrain axis