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The selective treatment has, therefore, been suggested to reduce the ecological impact, but maintain antiparasitic effectiveness through mitigation strategies such as specific selective treatment, timing in administration, and pasture management strategies (139141)

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coli isozyme in the RCSB PDB, including structures of true reaction intermediates.[21, 22] A majority of the mechanistic insight gained from studying AAT has been applicable to other PLP dependent enzymes, especially aminotransferases.[12, 17, 2335] In recent years, we have again turned to AAT to test basic ideas in PLP and protein chemistry