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J Agron Crop Sci

These supplements are taken orally, absorbed through the digestive system, and then processed by the body

If there is a lack of cobalamin in the body, methylmalonyl CoA accumulates, which presumably leads to the neurological manifestations of B12 deficiency.[4][7][9][12] The replenishment with parenteral cyanocobalamin causes a rapid and complete improvement of megaloblastic anemia and gastrointestinal symptoms caused by vitamin B12 deficiency

Generally, COX-2 participates in the synthesis of arachidonic acid derivatives, including prostaglandin E2, which is related to carcinogenic processes (Williams et al., 1999