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On the day 27th of postnatal development, animals of both genders were divided into 2 equal subgroups which from that time, for the next 33 days, were fed either with the ketogenic or standard laboratory fodder

Therefore, the identification of new drugs for this disease is indispensable

At the hormonal level, ketogenesis is strongly regulated by insulin, as it inhibits the breakdown of stored fats in adipocytes and promotes glucose uptake and utilization, leading to elevated levels of inhibitors of fatty acid oxidation and KBs production, such as succinyl-CoA and malonyl-CoA (Johnston and Alberti, 1982)

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