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doi: 10.1038/nature10812 29 CoxC

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More specifically, it causes the active forms to convert to cyanocobalamin, causing a functional deficiency

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Elle peut se manifester notamment par des dmangeaisons, une urticaire, un eczma, une rougeur de la peau, un dme (gonflement), pouvant tre svres, un dme gnralis, un brusque gonflement du visage et du cou (dme de Quincke), voire un malaise intense et brutal avec chute de la pression artrielle (choc)