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188 A meta-analysis of 19 randomized placebo-controlled trials including 1,683 patients found that melatonin supplementation improved sleep quality, increased total sleep time, and decreased sleep latency

10.1186/s12902-022-00947-2 78

Berg CP, Engels IH, Rothbart A, Lauber K, Renz A, Schlosser SF, et al

Three different oxygen-induced radical species in endothelial nitric-oxide synthase oxygenase domain under regulation by l-arginine and tetrahydrobiopterin