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The honest answer depends on your goal and how consistently you apply

doi: 10.1001/jamaoncol.2018.4224 195 DirixLYTakacsIJerusalemGNikolinakosPArkenauH-TForero-TorresAet al

All rotation datasets were collected taking 2-min integrated exposures over oscillations of 0.5 per exposure totaling approximately 26 h of data collection per crystal, at a detector distance of either 78 or 74 mm