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It was observed from the study that the probability of developing SCC within three years of treatment is greatly reduced by a brief course of calcipotriol with 5-FU treatment on the face and scalp

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However, the therapeutic use of cisplatin is limited by its irreversible side effects, including transcription inhibition, cell cycle arrest, generation of reactive oxygen species (ROS), and apoptosis [3]

A causal relationship is suggested by experiments with fecal microbiota transplantation (FMT)