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Several SNPs located in the genes for cystathionine -ligase (CTH), alcohol dehydrogenase 5, GCL and glutaredoxin showed significant or suggestive associations with autism spectrum disorders

Due to its function in maintaining CNS metal homeostasis and the established link between metal dyshomeostasis and neurodegenerative diseases 6,7,21,22 , MT3 represents an important target for investigation in ALS and MS