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Patient support There are several organisations that patients can be signposted to: Acknowledgements The authors would like to thank Shiva T Radhakrishnan, clinical research fellow (IBD), Imperial College Healthcare NHS Trust, for his support and guidance in writing this article

Research suggests that megadoses of two milligrams per day are safe for correcting a vitamin B12 deficiency

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Worked example: semaglutide escalation A 5 mg semaglutide vial reconstituted with 1.5 mL of bacteriostatic water gives a concentration of 3.33 mg/mL