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Common temporary effects may include: These effects usually improve within a few days

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Nonetheless, due to biological and physiological differences between a small animal model and humans, such as a thinner cartilage, possible spontaneous healing of defects, biomechanics, and physical loading in small animals, thus, an additional chondral defect repair study using minipigs should be conducted to confirm these effects

Despite the fact that the process of drug development from natural products is time-consuming, their efficacy has been shown to be effective over an extended period of time