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On the other hand, its high reactivity also contributes to the uncontrolled removal of electrons, which underlies pathological cell damage through the propagation of highly reactive oxygen-containing molecules

Melatonin maintains metal ion homeostasis, inhibiting programmed cell death by upregulating expression of the copper transporter protein ATP7B and that of the iron death inhibitor GPX4 [120]

Support the skin's natural wound healing processes, making it exceptional for addressing micro-damage and improving overall texture

Given the limitations of current single-target therapies, interest has grown in natural products as promising multi-target agents for modulating AD pathology (Zhang et al., 2024)