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Biochemical Society Transactions 33:13901393 Hwang C, Sinskey AJ, Lodish HF (1992) Oxidized redox state of glutathione in the endoplasmic reticulum

Although rare, mutations in TFR-2 may be the leading cause of hemochromatosis in the Asia Pacific region where the I238M variant of TFR2 (previously reported as a polymorphism) has an allele frequency of 7% [18,19,20]