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MOTS-c: How Mitochondrial and Cellular Energy Therapies Are Different Patients who feel tired, metabolically stuck, slower to recover, or less resilient with age often start searching for therapies

Adults under 60, rising to 20% in those over 60 Special flag / patients also taking metformin should monitor B12 closely due to documented depletion Key lab threshold / serum B12 0.4 mol/L) typically start with 1,000 mcg oral daily for 1 to 3 months, then reassess

Research has shown that individuals with recurrent aphthous stomatitis (RAS)characterised by repeated mouth ulcer episodesoften present with lower serum B12 levels compared to healthy controls

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