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FIGURE 2 Functional analysis of the STAR mutation in vitro Plasmids containing wild-type or mutated Q258*, S186R, or Q258*/S186R-STAR were transfected into COS-7 cells

Involvement of lactylation in physiology Lactate is an essential substance for various cellular physiological functions, playing a crucial regulatory role in energy metabolism, signal transduction, and maintaining microenvironment homeostasis