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Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates

The Dynamic Duo: L-Carnitine & CLA L-Carnitine: The Fat-Burning Catalyst: L-Carnitine is a naturally occurring amino acid that plays a vital role in energy production

24 Besides, NADPH acts as the reducing reagent for 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), the rate-limiting enzyme of the mevalonate pathway, which leads to the synthesis of cholesterol and nonsterol isoprenoids