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Description

49(1) 143 | DOI : 10.1165/rcmb.2012-0515OC A.D

Retinoic acid serves as a signaling molecule that modulates gene transcription by interacting with nuclear receptors, such as retinoic acid receptors (RARs) and retinoid X receptors (RXRs), and chromatin-modifying enzymes, including histone acetyltransferases (HATs) and histone deacetylases (HDACs) [60]