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Published studies have documented measurable increases in BDNF expression in animal models following Semax administration, with some research reporting elevations exceeding 50% relative to baseline in specific brain regions

The frequently used diabetes medication metformin can also reduce the absorption of B12 in the small intestine

Ashwagandha has been demonstrated in research on human brain cells to counteract the harmful effects of -amyloid, which may contribute to neurocognitive impairment during HIV infection [185]