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HrGSTm1 relative expression was significantly higher in eggs than in larvae and adults

It is postulated herein that the detrimental activation of autoimmune T cells by glutamate in MS could lead to: (1) Cytotoxicity in the CNS: T cell-mediated killing of neurons and glia cells, which would subsequently increase the extracellular glutamate levels, and by doing so increase the excitotoxicity mediated by excess glutamate, (2) Release of proinflammatory cytokines, e.g., TNF and IFN that increase neuroinflammation

Minott JA, van Vloten JP, Yates JGE, Chan L, Wood GA, Viloria-Petit AM, et al

The human lung adenocarcinoma cell line A549 was purchased from Shanghai Institute of Cellular Biology of Chinese Academy of Sciences (Shanghai, China)