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This enzyme wastes a helpful molecule called nicotinamide (a form of vitamin B3) by turning it into something useless instead of recycling it into NAD+, think of NAD+ as the main battery fuel that powers your cells energy factories (mitochondria)

Following a nutrient dense diet will almost always help a person with thyroid disease, but you may need to modify the diet according to your food sensitivities

Long-term effects of folic acid and vitamin-B12 supplementation on fracture risk and cardiovascular disease: Extended follow-up of the B-PROOF trial

Gastrointestinal side effects from B12 supplements are typically mild, transient, and often related to inactive ingredients rather than the vitamin itself