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Na+K+-ATPase-mediated ion transport is crucial for maintaining the correct concentration of sodium in the lens, and an abnormal elevation of lens sodium has been implicated in the development of senile cataracts (41)

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Advances in high-resolution PET instrumentation will allow more accurate quantification of small brain regions, including the brainstem nuclei (raphe nuclei and locus coeruleus) that are vulnerable to early neurodegeneration, prior to widespread neuropathology, depression and cognitive deficits [342]

GST expression has been linked to oestrogen receptor status and also showed an inverse correlation, 16, 17, 18 but this is the first report in pre-chemotherapy locally advanced primary breast cancer