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Later, oxLDL (338) and MDA-LDL (248) were shown to compete with AcLDL for binding and uptake by macrophages, suggesting they were native ligands for MSR

In the context of the association between neuroinflammatory conditions and metabolic syndrome/type II diabetes (in which glutamate may pay a key role) , Stanford researchers (Winer et al, 2011) have demonstrated the effectiveness of Rituximab treatment in mice in an autoimmune model of type II diabetes : B cell effects on glucose metabolism are mechanistically linked to the activation of proinflammatory macrophages and T cells and to the production of pathogenic IgG antibodies

"PT-141: a melanocortin agonist for the treatment of sexual dysfunction." Annals of the New York Academy of Sciences 2003;994:96-102

Long-term side effects including blepharitis leading to discontinuation of ripasudil