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The upper layer of the biphasic ferrogel contains Fe 3 O 4 , while the lower layer consists of a porous and deformable region devoid of Fe 3 O 4 [386]

High-impact variants, such as mutations in SHANK3, MECP2, TSC1/2, and SCN2A, disrupt synaptic signaling and cortical development

It has been shown to upregulate the expression of genes involved in lipid clearance while activating AMP-activated protein kinase (AMPK) and downregulating sterol regulatory element-binding protein 1c (SREBP-1c), a transcription factor central to hepatic lipogenesis

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