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Primers used listed in Table 1

Ursodeoxycholic acid (UDCA) and its taurine conjugate, tauroursodeoxycholic acid (TUDCA), are well-established for their cytoprotective and anti-inflammatory properties (133), while potentially mediating anti-inflammatory effects in colonic inflammation through FXR activation and M2 macrophage polarization (100), direct cytoprotection) underscore their therapeutic versatility in modulating immune responses