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B12 deficiency symptoms include (2, 3): Megaloblastic anemia Fatigue and weakness Constipation Loss of appetite and weight loss

Improved insulin sensitivity also reduces the risk of developing metabolic diseases and supports better overall metabolic health

In diet-induced obese (DIO) mouse models, 5-Amino-1MQ treatment produced significant reductions in body weight, white adipose tissue mass, and adipocyte cell size without significant effects on food intake suggesting a metabolic rather than appetite-suppressing mechanism