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Grouping and read-across approaches for risk assessment of nanomaterials

Eighteen compounds, accounting for 81.87%-98.87% of the total essential oil content, were identified in Salvia nemorosa (Table 3)

These finding are corroborated by Mummichog analysis, which showed substantial dysregulation of pathways involved in the metabolism of amino acids/secondary metabolites and glyoxylate/dicarboxylate in both the supernatant and cellular extract fractions (Fig

This has led to interest in NAC for conditions like systemic lupus erythematosus (SLE), where a small RCT found that NAC (2.4-4.8 g/day) improved disease activity scores and reduced anti-dsDNA antibody levels (Lai et al., Lupus, 2012) [42]