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The tissue and cell disruption during processing (e.g., mixing, cutting, crushing, freezing/thawing, and high pressure treatment) makes native polyglutamyl folates accessible for endogenous conjugases (-glutamyl hydrolases) and results in the hydrolysis to monoglutamyl folates in vegetables (e.g., leeks, cauliflower, broccoli, spinach, soybeans, green beans, cowpea leaves, turnip, and carrot) and fruits (e.g., orange, papaya, sweet cherry, strawberry, and blackberry)

doi: 10.3389/fendo.2021.682625 Summary Keywords -cells, endoplasmic reticulum, stress, insulin, diabetes mellitus, hPSC-derived -cells Citation Diane A, Allouch A, Mu-U-Min RBA and Al-Siddiqi HH (2024) Endoplasmic reticulum stress in pancreatic -cell dysfunctionality and diabetes mellitus: a promising target for generation of functional hPSC-derived -cells in vitro