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T cell receptors (TCRs) provide a recognition signal for T cells complemented by a co-stimulatory signal that can provide an on/off signal to regulate the activation of T cells

The Griess reagent (1% sulphanilamide, 2% phosphoric acid, and 0.1% naphthyl ethylene diamine dichloride) was used as the standard

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To facilitate comparison across tumor types, we summarized representative DTP-associated molecular markers and transcriptional signatures across major cancer contexts ( Table 2 )