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A recent investigation propose that LDHB mediates a complex three-step reaction cycle, wherein reducing equivalents are transferred from lactate to reduced CoQH2, with NAD+ serving as a cycling cofactor (124)

3.2 Post-Translational Modifications of p53 and Their Impacts on p53-Mediated Ferroptosis The paradigm shift concerning the role of p53 in ferroptosis prompted us to investigate how and when p53 promotes or suppresses ferroptosis

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