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Values are expressed as means SE

doi: 10.1017/S0007114514002037

For example, histone deacetylase (HDAC) inhibitors like trichostatin-A and valproic acid increase Nrf2 expression by enhancing histone acetylation at the Nrf2 promoter, thereby restoring the Nrf2-mediated antioxidant defense and safeguarding cells from oxidative stress damage (163)