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Nature Protocols 7 , 872881 (2012) Cairns, R

F., Tao, H., Linton, E

Graphical abstract Similar content being viewed by others Background Parkinsons disease (PD) is a progressive complicated central nervous system degenerative disorder, distinguished by bradykinesia, resting tremors, rigidity, and gait abnormality [1] which is attributed to neurodegeneration and dopaminergic neurons necrosis in substantia nigra pars compacta (SNpc), resulting in a decline of dopamine release to striatal terminals [2]