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Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain

These include hydroxyl, superoxide and nitric oxide radicals, hydrogen peroxide, singlet oxygen, hypochlorous acid (HOCl), and peroxynitrite (Figure 1)

FDL@TP reduced the expression of cGAS and STING, which further led to the reduction in TNF-, IL-1, and IL-6 production (70)

Furthermore, the integration of metabolomics with advanced platforms such as machine learning, green chemistry principles, and microfluidic innovations is discussed as a transformative direction for future pesticide residue monitoring