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The use of metformin for the management of blood sugar levels can deplete levels of Vitamin B12 in the body

Next, we scanned promoter regions of all transcripts in the transcriptome for known motif instances using the motif scanning tool Find Individual Motif Occurrences (FIMO) [ 33 ], and used a hypergeometric test to determine the level of enrichment of each instance among transcripts in DAVID pathway clusters (Figure 7A, workflow diagram)

While an overdrive of GABAergic signaling slows the development, the overactivity of glutamatergic signaling causes excitotoxicity [1]