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Description

Clonal dynamics reveal two distinct populations of basal cells in slow-turnover airway epithelium

Let op: Wij verkopen onderstaande research chemicals uitsluitend voor in-vitro studies

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The cytotoxic effect of TMZ is primarily exerted by methylation of O 6 position of guanine ( O 6 -meG) which escapes O 6 -meG-DNA-methyl transferase (MGMT) repair resulting in futile cycles of mismatch repair leading to DSBs and triggering cell cycle arrest and apoptosis 32