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Description

Disorders of lysosomal acidificationthe emerging role of v-ATPase in aging and neurodegenerative disease

In 2013, Varnagy et al

To shed light onto this surprising finding, atomistic details of the above-mentioned diverse transport processes were investigated by MD simulations using the homology model of rat Mrp1 in complex with its docked ligands GSH, GSSG and/or ritonavir