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10.1016/j.fct.2022.112823 187 WangL.DongX

Understanding Glutathiones Role in Redox and Neurotransmission Systemic inflammation and oxidative stress have been observed alongside depressive disorders and certain anxiety-related presentations

Replenishing GSH levels has been shown to protect the brain, slow neurodegeneration, and even repair damage

This reaction weakens the binding between Keap1 and NRF2, allowing NRF2 to escape the negative regulation of Keap1 and avoiding ubiquitination and degradation