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Upon completion of viral assembly, NA cleaves SA residues on the host cell surface to promote the release of progeny virions and their spread to neighboring cells, whereas proteolytic cleavage of HA by host proteases such as transmembrane serine protease 2 (TMPRSS2) is required for efficient viral release (13)

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4NQO enhances differential activation of DNA repair proteins in HPV positive and HPV negative HNSCC cells

EM maps and models generated in this study, of CBS basal state (EMD-19735, PDB 8S5H, EMD-19736, PDB 8S5I, EMD-19737, PDB 8S5J, EMD-19738, PDB 8S5K), degraded CBS tetramer (EMD-19739, PDB 8S5L) and CBS + SAM activated state (EMD-19740, PDB 8S5M, EMD-19741, EMD-19742), have been deposited to the Electron Microscopy Data Bank (EMDB) and Protein Data Bank (PDB)