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Factors like high-temperature cooking methods, sedentary lifestyles, and diets rich in processed foods elevate AGE production, intensifying these compounds' impact

Importantly, along with an induction of HIF1, in SCD erythroblasts cultured in the absence of hemin, we detected a significantly decreased CBS expression under hypoxia compared to normoxia (Supplementary Fig

Although conducted in breast cancer cell lines, recent studies have confirmed similar metabolic processes in prostate cancer (77).These findings highlight tumor-specific adaptations in ammonium metabolism, emphasizing its role in sustaining proliferation and metabolic flexibility