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Figure 2 3.4

The peptide's effects on metabolic rate and energy expenditure in animal models contribute to these observations, with research showing alterations in energy utilization and substrate metabolism patterns in experimental systems

Gastrointestinal symptoms such as abdominal pain and diarrhoea secondary to colitis are classic ipilimumab-related irAEs that manifest as loose stool, abdominal pain, haematochezia and fever