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coli cells were used to evaluate Humira IgG expression, SHuffle cells with their oxidizing cytoplasm harboring empty vectors as a control for background (MB6209), SHuffle cells expressing Humira IgG (MB4135), and SHuffle2 cells co-expressing human PDI-GPx7 (MB6201)

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Correlation between methylation levels of differentially methylated loci (DML) at endpoint B compared to endpoint A and CCL3 gene expression levels from the same cultures were tested with Pearson or Spearman correlation for parametric or nonparametric distributions, respectively