glutathione-responsive prodrug

glutathione-responsive prodrug Frontiers Glutathione‐triggered prodrugs: Design strategies, potential

Name: glutathione-responsive prodrug Frontiers Glutathione‐triggered prodrugs: Design strategies, potential
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Glutathionetriggered prodrugs: Design strategies, potential applications, and perspectives Zhao 2024 Medicinal Research Reviews Wiley Online Library Activatable theranostic prodrug scaffold with tunable drug release rate for sequential photodynamic and chemotherapy Wang 2024 Smart Molecules Wiley Online Library Balancing Stability and Payload Release in Glutathione Responsive PROTAC Prodrugs Targeting Prostate Cancer JACS Au Glutathione responsive prodrug conjugates for image guided combination in cancer therapy ScienceDirect

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10.1007/s10533-018-0458-6 [DOI] [Google Scholar] Zhu XM, Hackl S, Thaker MN, Kalan L, Weber C, Urgast DS, Krupp EM, Brewer A, Vanner S, Szawiola A, Yim G, Feldmann J, Bechthold A, Wright GD, & Zechel DL (2015)

ITC analysis of a PL-containing synthetic peptide from DENND4C established direct binding to recombinant VPS29 with an affinity ( K d ) of 15.4 M, that was blocked by mutation of the PL motif or by the addition of a competing VPS29-binding macrocyclic peptide RT-D1 (Fig