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For instance, research shows that HRD tumor cells, after platinum treatment, may evade drug effects by restoring HRR functionality or upregulating multi-drug resistance-related genes ( Furthermore, changes in the tumor microenvironment, intercellular signaling, and gene expression alterations can also promote the development of resistance

Kargl, J

In addition, since atrial fibrillation increases ischemic stroke risk, anticoagulant medications such as warfarin (Coumadin) or dabigatran (Pradaxa) are used to prevent blood clot formation in people with this arrhythmia (Gallego 2012