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None of those uses have been approved by the FDA

We also found that the level of ATGL, an enzyme involved in TG hydrolysis, was significantly decreased in HepG2 cells treated with PA load or/and riboflavin deficiency after PPAR silencing

In murine models, combining the TH-302 nanodrug with PD-1 blockade significantly enhanced antitumor efficacy, leading to greater tumor regression and prolonged survival compared to either treatment alone (306)