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The field of the invention relates generally to quinoline derived small molecule inhibitors of nicotinamide N-methyltransferase (NNMT), the preparation thereof, and the uses thereof

Treatment response in vitamin B12 deficiency depends on the chosen vitamin B12 preparation

Low consumption of B12 can lead to deficiency, where B12 levels become too low to meet the bodys needs

It must be determined that it meets at least two of the following three criteria: It has the potential to enhance or enhances sport performance It represents an actual or potential health risk to the athletes It violates the spirit of sport WADA also published: The 2025 Monitoring Program, which includes substances that are not on the List , but that WADA wishes to monitor in order to detect potential patterns of misuse in sport